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【Symptoms】: When there is difficulty in breathing, dry cough. Since then often due to a cold, acute respiratory infection-induced and aggravated, and the increase was progressive. A gradual increase in breathing fast but no wheezing, irritating cough or sputum, a few had fever, hemoptysis, or chest pain. Action after a serious while asthma, palpitation out sweating, malaise, weight loss, lip Violet cyanosis and clubbed fingers (toes). For physical examination in the next wet rale lung field could be heard. In the concurrent pulmonary heart disease with pulmonary second sound when hyperthyroidism, jugular vein Nu Zhang, hepatomegaly, and lower limb swelling.

【Pathology】: interstitial pneumonia is a lung interstitial tissue inflammation, inflammation mainly affects the bronchial wall, alveolar wall, especially around the bronchial vessels, and alveolar intervals around the interlobular connective tissue, and, Duocheng necrotic lesions.
Interstitial pneumonia, also known as interstitial lung disease, diffuse lung diseases, as the disease name, and only 10 years of history, by definition it is the pulmonary interstitial lesions. Interstitial pneumonia is not a single disease, but the general term for a large class of diseases, some hundred species are known to cause a small part had been identified, such as pneumoconiosis, drug-induced pneumonia, radiation pneumonitis, etc.; but there are a considerable number of causes unknown, such as idiopathic pulmonary fibrosis, sarcoidosis and so on. Interstitial pneumonia may be referred to as "pneumonia", but not primarily by bacteria, viruses and other microbial infections made; idiopathic pulmonary fibrosis (idiopathic pulmonary fibrosis, IPF) is a kind of unknown cause in order to diffuse alveolar inflammation and alveolar structural disorder and ultimately lead to pulmonary fibrosis is characterized by disease. According to duration of acute, subacute and chronic of the points, the so-called Hamman-Rich syndrome is of acute type, clinical more to see is the sub-acute and chronic type. European scholars said that this disease for more than cryptogenic fibrosing alveolitis (cryptogenicfibrosingalveolitis, CFA).