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WHO H1N1 influenza vaccine the problem

Updated: Thursday, Nov 05,2009, 12:40:05 PM
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Influenza A H1N1 influenza is still spreading in many countries, it is now one of the issues most concerned about is the response to the influenza virus vaccine when they appear. World Health Organization on its official Web site for issues related to the vaccine made answer:

1, there is no single effective against influenza A H1N1 influenza vaccine?

There is no, but the vaccine-related research and development is under way. When an influenza virus is epidemic, the influenza vaccine for this virus usually contain has been killed (ie, inactivated), or reduce the toxicity of influenza viruses, so that makes the body can produce antibodies against the virus, so that the immune system ready to deal with the real flu virus strikes.

To get the best preventive vaccine to reach protective efficacy, the vaccine contained the virus is pandemic virus must be as close as possible. Currently circulating influenza A H1N1 influenza virus is a new virus, have not yet produced a virus that contains the new influenza vaccine. The development of a new influenza vaccine usually takes 5 to 6 months time-consuming.

Second, if there is pandemic influenza vaccine production for the impact?

At present, the global influenza pandemic warning level remained at five. If the WHO announced the warning level raised to six, namely, that a virus in more than one regional large-scale epidemic, a global pandemic. But this in itself does not mean that automatically require vaccine manufacturers to immediately halt the production of conventional and begin production of seasonal influenza vaccine for the prevention and control of influenza pandemic vaccines.

Seasonal influenza also may lead to a severe influenza pandemic, so the future when a new influenza pandemic, WHO will consider several important factors, an integrated, such as the epidemiology, severity of the disease itself and so on, to decide When a formal proposal to the vaccine manufacturers, so that the latter began mass production of new vaccines.

Third, the vaccine for the control of influenza pandemics in the end more important?

Influenza pandemic, the vaccine is one of the most valuable means of protection. Other prevention and control methods also include the use of antiviral drugs, control of public social activities and maintaining personal hygiene.

4, the existing prevention of seasonal influenza vaccine against influenza A H1N1 influenza do?

To address this issue, there are already sufficient scientific evidence is not enough, but preliminary studies have shown that in dealing with influenza A H1N1 influenza, the preventive effect of seasonal influenza vaccine for people little or no protection.

5, WHO has taken measures to promote the Influenza A H1N1 influenza vaccine?

WHO received the first case of human infection with influenza A H1N1 influenza report, as one of the WHO Collaborating Centers for Disease Control and Prevention immediate action to begin preparation for the development of a vaccine candidate viruses. WHO, with both vaccine manufacturers around the world in consultation, in order to develop a vaccine against influenza A H1N1 influenza provide all the necessary materials. WHO has also linked with national health regulatory authorities to ensure that new vaccines meet all safety standards in the future as quickly as possible available to the various countries.

6, developed for a new pandemic influenza vaccine What are the steps?

Development of H1N1 influenza in view of the current influenza vaccine must be approved through the WHO's vaccine development process. Currently, a candidate for vaccine development by the U.S. CDC strain of the virus to complete the identification. Preparation of these strains, once completed, the world interested in its use and development agencies in completing the necessary formalities can be acquired, for vaccine production. It is estimated that in mid-May of this year, vaccine manufacturers will be able to obtain strains.

7, the fastest when it can produce a vaccine against the Influenza A H1N1 influenza?

Identified from the initial pandemic influenza strains to the first dose of the vaccine market, usually takes 5 to 6 months. Production of vaccines in the business at the same time, national health regulatory authorities will also be synchronized to start the approval process. To ensure vaccine quality and safety circumstances, the national regulatory authorities will fast-track vaccine.

8, in the influenza A H1N1 influenza vaccine is successful, global production capacity be?

Influenza A H1N1 influenza vaccine in the successful development of an estimated global annual produce at least 1 billion to 2 billion this vaccine.

WHO will follow the development of an influenza pandemic, when given adequate information, it will define who are at high risk of influenza, countries may refer to decided to give priority vaccination groups of people, so that the limited vaccine supply to maximize the protective effect.

9, if the influenza A H1N1 influenza virus six months after the mutation, and now vaccines will be Still Useful?

To predict the changes in influenza A H1N1 influenza virus is still too early, but the WHO and other relevant agencies are closely monitoring the virus any change in the future once the virus is a major change, this close, continuous monitoring will help to guide rapid response.

Tags: influenza H1N1 vaccine

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